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BIOPROCESS DIGITAL PROFESSIONAL COURSES
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Introduction to microbial fermentations engineering

Fermentation kinetics, simulation, operation and optimization

ONLINE COURSE: On-demand

COURSE FEE: 350 € per session

COURSE ORGANIZATION

Course organized in 3 sessions

Scheduling: suggested one session per week

Effort: 3 - 6 hours per session

COURSE DESCRIPTION

This introductory course provides a solid foundation in microbial fermentation engineering, designed for students and professionals new to the field of bioprocess engineering. It covers core principles for simulating, scaling-up, and optimizing microbial fermentation processes across diverse industrial applications.

Through practical examples, including aerobic and anaerobic fermentations for the production of cells, metabolites and proteins, participants will explore methodologies in kinetic analysis, process simulation and fermentation optimization.

INSTRUCTOR

  • Jean-Marc Engasser, BioProcess Digital

DIGITAL LEARNING

  • Learning platform with course resources

  • Live or recorded slideshow presentations

  • Case studies on spreadsheet templates 

  • Online collective or one-to-one tutoring

COURSE PROGRAM

SESSION 1: STOICHIOMETRY AND KINETICS OF MICROBIAL FERMENTATIONS 

Stoichiometry and kinetics of of industrial fermentation processes for the production of cells, metabolites and proteins.

Globalf fermentation rates and microbial specific rates: cells growth, substrates consumption, products formation.

SESSION 2: MODELING AND SIMULATION OF MICROBIAL FERMENTATIONS 

Key biological and physical phenomena influencing fermentations: cellular reaction, oxygen transfer, medium dynamics.

Development of simulation models integrating mass balances with cellular rates laws and oxygen transfer law. 

SESSION 3: OPTIMAL OPERATION OF MICROBIAL FERMENTATIONS 

Comparative analysis of batch, continuous and fed-batch operation modes: principles, performances, limitations.

Strategies for optimizing process variables to maximize fermentor productivity. 

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Capture d’écran 2020-05-24 à 19.23.40 co
Nancy, France
© 2025 BioProcess Digital, Inc
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