BIOPROCESS DIGITAL PROFESSIONAL COURSES

Introduction to microbial fermentations engineering
Fermentation kinetics, simulation, operation and optimization
ONLINE COURSE: On-demand
COURSE FEE: 350 € per session
COURSE ORGANIZATION
Course organized in 3 sessions
Scheduling: suggested one session per week
Effort: 3 - 6 hours per session
COURSE DESCRIPTION
This introductory course provides a solid foundation in microbial fermentation engineering, designed for students and professionals new to the field of bioprocess engineering. It covers core principles for simulating, scaling-up, and optimizing microbial fermentation processes across diverse industrial applications.
Through practical examples, including aerobic and anaerobic fermentations for the production of cells, metabolites and proteins, participants will explore methodologies in kinetic analysis, process simulation and fermentation optimization.
INSTRUCTOR
-
Jean-Marc Engasser, BioProcess Digital
DIGITAL LEARNING
-
Learning platform with course resources
-
Live or recorded slideshow presentations
-
Case studies on spreadsheet templates
-
Online collective or one-to-one tutoring
COURSE PROGRAM
SESSION 1: STOICHIOMETRY AND KINETICS OF MICROBIAL FERMENTATIONS
Stoichiometry and kinetics of of industrial fermentation processes for the production of cells, metabolites and proteins.
Globalf fermentation rates and microbial specific rates: cells growth, substrates consumption, products formation.
SESSION 2: MODELING AND SIMULATION OF MICROBIAL FERMENTATIONS
Key biological and physical phenomena influencing fermentations: cellular reaction, oxygen transfer, medium dynamics.
Development of simulation models integrating mass balances with cellular rates laws and oxygen transfer law.
SESSION 3: OPTIMAL OPERATION OF MICROBIAL FERMENTATIONS
Comparative analysis of batch, continuous and fed-batch operation modes: principles, performances, limitations.
Strategies for optimizing process variables to maximize fermentor productivity.