BIOPROCESS DIGITAL PROFESSIONAL COURSES

Introduction to microbial fermentation processes
Industrial fermentation processes. Fermentors technologies and scale-up. Batch, continuous, fed-batch and perfusion operations. Fermentations costs
ONLINE COURSE
On-demand
COURSE FEE
350 € per session
COURSE ORGANIZATION
Course organized in 8 sessions
Sessions can be taken individually
Sessions scheduling: suggested one session per week
Effort: 4 - 6 hours per session
COURSE DESCRIPTION
The course provides a comprehensive overview of industrial fermentation processes, including their technologies, operations, scale-up, and cost analysis. It introduces the kinetics of microbial transformations and of oxygen transfer. It compared the fermentations batch, continuous, fed-batch, and perfusion operations.
The course features a combination of methodological presentations, fermentation case studies, and quizzes.
INSTRUCTORS
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Jean-Marc Engasser, BioProcess Digital
DIGITAL LEARNING
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Learning platform with course resources
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Live or recorded slideshow presentations
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Case studies on spreadsheet templates with guides and corrections
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Online quizzes
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Online collective or one-to-one tutoring
COURSE PROGRAM
SESSION 1: INDUSTRIAL FERMENTATION PROCESSES
Microorganisms, media, products. Upstream and downstream operations. Fermentors technologies and operations
SESSION 2: MICROBIAL KINETICS
KInetic analysis in batch and continuous fermentors. Microbial kinetic laws
SESSION 3: FERMENTORS AERATION AND OXYGEN TRANSFER
Fermentors aeration technologies. Oxygen solubility and transfer kinetics. Determination of oxygen transfer coefficient
SESSION 4: FERMENTATIONS SIMULATION, SCALE-UP, AND COST OPTIMIZATION
Fermentations influencing phenomena and simulation models. Fermentors scale-up. Cost evaluation and optimization
SESSION 5: BATCH FERMENTATIONS
Batch fermentations principles, kinetics, productivity limitations, and operational optimization
SESSION 6: CONTINUOUS FERMENTATIONS
Continuous fermentations principles, kinetics, productivity limitations, and operational optimization
SESSION 7: FED-BATCH FERMENTATIONS
Fed-batch fermentations principles, kinetics, productivity limitations, and operational optimization
SESSION 8: PERFUSION HIGH-DENSITY FERMENTATIONS
Perfusion fermentations principles and technologies, kinetics, productivity limitations, and operational optimization