top of page
BIOPROCESS DIGITAL PROFESSIONAL COURSES
shutterstock_524613634_edited.jpg

Introduction to microbial fermentation processes

Industrial fermentation processes. Fermentors technologies and scale-up. Batch, continuous, fed-batch and perfusion operations. Fermentations costs

ONLINE COURSE

On-demand

COURSE FEE

350 € per session

COURSE ORGANIZATION

Course organized in 8 sessions

   Sessions can be taken individually

Sessions scheduling: suggested one session per week

Effort: 4 - 6 hours per session

COURSE DESCRIPTION

The course provides a comprehensive overview of industrial fermentation processes, including their technologies, operations, scale-up, and cost analysis. It introduces the kinetics of microbial transformations and of oxygen transfer. It compared the fermentations batch, continuous, fed-batch, and perfusion operations. 

The course features a combination of methodological presentations, fermentation case studies, and quizzes.

INSTRUCTORS​

  • Jean-Marc Engasser, BioProcess Digital

DIGITAL LEARNING​

  • Learning platform with course resources

  • Live or recorded slideshow presentations

  • Case studies on spreadsheet templates with guides and corrections

  • Online quizzes

  • Online collective or one-to-one tutoring

COURSE PROGRAM

SESSION 1: INDUSTRIAL FERMENTATION PROCESSES

Microorganisms, media, products. Upstream and downstream operations. Fermentors technologies and operations

​

SESSION 2: MICROBIAL KINETICS

KInetic analysis in batch and continuous fermentors. Microbial kinetic laws

​

SESSION 3: FERMENTORS AERATION AND OXYGEN TRANSFER

Fermentors aeration technologies. Oxygen solubility and transfer kinetics. Determination of oxygen transfer coefficient 

​​

SESSION 4: FERMENTATIONS SIMULATION, SCALE-UP, AND COST OPTIMIZATION 

Fermentations influencing phenomena and simulation models. Fermentors scale-up. Cost evaluation and optimization

​

SESSION 5: BATCH FERMENTATIONS

Batch fermentations principles, kinetics, productivity limitations, and operational optimization

​

SESSION 6: CONTINUOUS FERMENTATIONS 

Continuous fermentations principles, kinetics, productivity limitations, and operational optimization

​

SESSION 7: FED-BATCH FERMENTATIONS

Fed-batch fermentations principles, kinetics, productivity limitations, and operational optimization

​

SESSION 8: PERFUSION HIGH-DENSITY FERMENTATIONS 

Perfusion fermentations principles and technologies, kinetics, productivity limitations, and operational optimization

bottom of page