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BIOPROCESS DESIGN AND OPTIMIZATION PROJECTS

BioProcess Digital teaches the bioprocess engineering concepts and methodology 

through case studies projects developed on spreadsheet simulators

CASE STUDY PROJECTS

Projects objectives

  • Determine bioprocess mass balances, energy consumptions, equipment sizes

  • Optimize bioreactors batch, continuous and fed-batch operations

  • Evaluate and reduce bioprocess cost

  • Evaluate and reduce bioprocess environmental impacts

Examples of projects

Project Enzyme.png
Project Yeast.png
Project Glutamate_edited.jpg

Design, cost and environmental optimization of a fermentation process

  • Process material balance and energy consumption

  • Cost evaluation of the production process

  • Environmental impacts of the process​​

Digital scale-up and optimization of a yeast fermentation 

  • Modeling-simulation of the yeast fermentation

  • Scale-up and optimization of the yeast fed-batch fermentation

Simulation, scale-up, optimal operation of the glutamic acid fermentation

  • Kinetic analysis, modeling-simulation of the fermentation

  • Cost evaluation of the fermentation process

  • Optimisation of the batch, continuous and fed-batch fermentations

BIOREACTOR AND BIOPROCESS SPREADSHEET SIMULATORS

  • Develop and use spreadsheet simulators to design and optimize bioprocesses

Examples of spreadsheet simulators

Cells bioreactor.png

Animal cell bioreactor simulator

Simulator to learn how to optimize a batch bioreactor for the production of animal cells

Capture d’écran 2020-05-24 à 19.23.40 co
Nancy, France
Email : contact@bioprocessdigital.com
© 2025 BioProcess Digital, Inc
Online courses
Introduction to bioprocess design, scale-up and simulation
Bioprocess engineering basic principles
Introduction to microbial fermentation engineering
Digital scale-up and optimization of microbial fermentations
Case study in Digital scale-up and optimization of fermentation processes
Introduction to enzymatic bioconversion processes
Simulation, scale-up, and optimization of soluble and immobilized enzyme bioreactors
Introduction to animal cells culture processes
Simulation, scale-up, and optimal operation of suspended and adherent animal cells bioreactors
Design, scale-up, and cost evaluation of recombinant proteins production
Bioprocess design and cost evaluation
Introduction to bioprocess Life Cycle Assessment
Life Cycle Assessment of bioprocesses and byproducts
 
Online diploma
DU Université de Lorraine, ENSAIA
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