Introduction to bioprocess design, scale-up, and simulation

Bioprocess engineering scope and digital methodology

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Bioprocess engineering basic principles

Material and energy balances, fluid flow and residence time distribution, mass and heat transfer, enzymatic and cellular kinetics

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Introduction to microbial fermentation processes

Industrial fermentation processes. Fermentors technologies and scale-up.

Batch, continuous, fed-batch and perfusion operations. Fermentations costs

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MICROBIAL FERMENTATION PROCESSES

Simulation, scale-up, and optimal operation of microbial fermentors

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Introduction to enzymatic bioconversion processes

Enzymes and whole-cells biocatalysts, industrial bioconversions, soluble and immobilized enzymes bioreactors, bioconversion costs

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ENZYMATIC BIOCONVERSION PROCESSES

Simulation, scale-up, and optimization of soluble and immobilized enzymes bioreactors 

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Introduction to animal cell culture processes

Appplications, cells, media, kinetics, culture systems, bioreactors operations, purification, quality, stem cells technology

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ANIMAL CELL CULTURE PROCESSES

Simulation, scale-up, and optimal operations of suspended and adherent animal cell bioreactors 

 

ANIMAL CELL CULTURE PROCESSES

Design, scale-up, and cost evaluation of recombinant proteins production processes 

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Bioprocess design and cost evaluation

Material balance, energy consumption, equipment sizing, investment and production cost, uncertainty analysis, bioprocess optimization

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Life Cycle Assessment of bioprocesses and bioproducts

LCA scope and methodology, environmental impacts, material and energy inventories, impacts indicators, impacts allocation, comparative LCA