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BIOPROCESS DIGITAL PROFESSIONAL COURSES
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Design, scale-up and cost evaluation of recombinant proteins production processes

Animal cells culture processes

ONLINE COURSE

On-demand

COURSE FEE

300 € per session 

COURSE ORGANIZATION

Course organized in 3 sessions

Sessions scheduling: at your pace

Effort: 4 - 8 hours per session

COURSE DESCRIPTION

The course teaches the methodology for the design and cost evaluation of a monoclonal antibody production process by recombinant CHO cells. It involves the evaluation of the production and purification process material balance,equipment sizing, energy consumption, investment cost and antibody production cost.

INSTRUCTOR​

  • Jean-Marc ENGASSER, BioProcess Digital

DIGITAL LEARNING​

  • Learning platform with course resources

  • Live or recorded slideshow videos

  • Process design and cost evaluation on spreadsheet templates with self-corrections and guides

  • Online collective or one-to-one tutoring

COURSE PROGRAM

SESSION 1: ​PROCESS MATERIAL BALANCE​

  • Flowsheet of the mAbs production and purification process

  • Materials consumption of the upstream and downstream process sections

  • Antibodies and effluents productions

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SESSION 2: ​PROCESS EQUIPMENT SIZING AND ENERGY CONSUMPTION

  • Sizes of the bioreactor, membrane and chromatography equipment

  • Mechanical and thermal energy consumption

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SESSION 3: ​INVESTMENT AND PRODUCTION COST

  • Investment cost for the production plant

  • Materials, energy, equipement utilization and labor costs

  • Sensitivity analysis of the mAbs production cost

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